GENERATING NUCLEIC ACIDS WITH MODIFIED BASES USING RECOMBINANT TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE

Disclosed herein include methods of generating a single stranded deoxyribonucleic acid (ssDNA) scaffold comprising nucleotides with modified bases using a recombinant terminal deoxynucleotidyl transferase (TdT). The recombinant TdT can comprise an amino acid sequence that is at least 80% identical t...

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Hauptverfasser: PEISAJOVICH, Sergio, BRUSTAD, Eric, NIRANTAR, Saurabh Rajendra
Format: Patent
Sprache:eng ; fre ; ger
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