ANTI-TIGIT ANTIBODY AND PREPARATION METHOD AND APPLICATION THEREOF
Provided is a separated antigen-binding protein. The antigen-binding protein comprises at least one CDR in a heavy chain variable region VH, and the VH comprises an amino acid sequence shown in SEQ ID NO: 55. Also provided are an anti-TIGIT antibody, and a preparation method and an application there...
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| creator | CHEN, Shi XIE, Jianmei WEI, Xiaoyue CAI, Mingqing ZHU, Xiangyang YU, Haijia |
| description | Provided is a separated antigen-binding protein. The antigen-binding protein comprises at least one CDR in a heavy chain variable region VH, and the VH comprises an amino acid sequence shown in SEQ ID NO: 55. Also provided are an anti-TIGIT antibody, and a preparation method and an application thereof. The antigen-binding protein can specifically bind with a TIGIT antigen to block the binding of TIGIT and a ligand thereof, and can be used for preparing drugs for preventing or treating TIGIT-related diseases. |
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The antigen-binding protein comprises at least one CDR in a heavy chain variable region VH, and the VH comprises an amino acid sequence shown in SEQ ID NO: 55. Also provided are an anti-TIGIT antibody, and a preparation method and an application thereof. 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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ANTI-TIGIT ANTIBODY AND PREPARATION METHOD AND APPLICATION THEREOF |
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