SELECTION BY ESSENTIAL-GENE KNOCK-IN

Strategies, systems, compositions, and methods for efficient production of knock-in cellular clones without reporter genes. An essential gene is targeted using a knock-in cassette that comprises an exogenous coding sequence for a gene product of interest (or "cargo sequence") in frame with...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	TOMISHIMA, Mark James, MARGULIES, Carrie Marie, ZURIS, John Anthony, SOH, Chew-Li, MCAULIFFE, Conor Brian, MONETTI, Claudio, TONGE, Peter
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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