AFFINITY MATURED ANTI-LAP ANTIBODIES AND USES THEREOF

Provided herein are anti-LAP antibodies (e.g., recombinant humanized, chimeric, and human anti-LAP antibodies) or antigen binding fragments thereof which have therapeutically beneficial properties, such as binding specifically to LAP-TGFβ1 on cells but not to LAP-TGFβ1 in extracellular matrix, as we...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	HOLLINGSWORTH, Scott A, JUAN, Veronica M, HSIEH, Chung-Ming, YANG, Song, CASTOR, Michelle, CHEN, Ming-Tang, CHENG, Alan C, SHIDHORE, Madhura, MOORE, Renee C. T
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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