METHOD FOR SYNTHESIZING (S)-NICOTINE

Provided is a method for synthesizing (S)-nicotine, comprising: under the condition of a coenzyme circulation system, by using a coenzyme as a hydrogen donor, and by using imine reductase as a catalyst, catalyzing and reducing myosmine to (S)-nornicotine, and then subjecting (S)-nornicotine to a met...

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Hauptverfasser: HU, Jicheng, LI, Lingyu, CHEN, Zegcong, YUE, Yongtang, ZHENG, Hongjie, ZHU, Jianping, LIN, Wenqing, LIU, Xiaobo, WANG, Jianchong
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creator HU, Jicheng
LI, Lingyu
CHEN, Zegcong
YUE, Yongtang
ZHENG, Hongjie
ZHU, Jianping
LIN, Wenqing
LIU, Xiaobo
WANG, Jianchong
description Provided is a method for synthesizing (S)-nicotine, comprising: under the condition of a coenzyme circulation system, by using a coenzyme as a hydrogen donor, and by using imine reductase as a catalyst, catalyzing and reducing myosmine to (S)-nornicotine, and then subjecting (S)-nornicotine to a methylation reaction so as to obtain (S)-nicotine.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
VINEGAR
WINE
title METHOD FOR SYNTHESIZING (S)-NICOTINE
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