METHOD FOR OBTAINING ALPHA-1 PROTEINASE INHIBITOR

METHOD FOR OBTAINING ALPHA-1 PROTEINASE INHIBITOR

A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a solution of A1PI by concentrating an initial solution of A1PI by tangential flow filtration (TFF) against water. The final concentration of A1PI in the conce...

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Hauptverfasser: MCBRIDE, Dennis, REBBEOR, James, YUZIUK, Jeffrey, A, GRADY, George
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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creator MCBRIDE, Dennis
REBBEOR, James
YUZIUK, Jeffrey, A
GRADY, George
description A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a solution of A1PI by concentrating an initial solution of A1PI by tangential flow filtration (TFF) against water. The final concentration of A1PI in the concentrated solution is at least 110 mg/ml. The TFF can be carried out against water for injection (WFD).
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
title METHOD FOR OBTAINING ALPHA-1 PROTEINASE INHIBITOR
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