HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE

[Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequen...

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Hauptverfasser: TAKAHASHI, Kenichi, SAWAI, Naoki, YODEN, Eiji, EHARA, Takeru, HASHIMOTO, Hidehiko, TAKUWA, Masatoshi, OHUCHI, Masaki, NAKAMURA, Naoko, INABA, Shinnosuke, FUJIYAMA, Saki, MASUYA, Keiichi, BASHIRUDDIN, Nasir Kato
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creator TAKAHASHI, Kenichi
SAWAI, Naoki
YODEN, Eiji
EHARA, Takeru
HASHIMOTO, Hidehiko
TAKUWA, Masatoshi
OHUCHI, Masaki
NAKAMURA, Naoko
INABA, Shinnosuke
FUJIYAMA, Saki
MASUYA, Keiichi
BASHIRUDDIN, Nasir Kato
description [Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequence having substitutions, deletions, additions, and/or insertions of 1 to 10 amino acid residues (inclusive) in the amino acid sequence shown in SEQ ID NO: 1.
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language eng ; fre ; ger
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE
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