SYNTHESIS AND USE OF CLASS OF RESPIRATORY SYNCYTIAL VIRUS INHIBITORS

SYNTHESIS AND USE OF CLASS OF RESPIRATORY SYNCYTIAL VIRUS INHIBITORS

The present disclosure provides the synthesis and application of respiratory syncytial virus inhibitor, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer, solvate, prodrug or isotope label thereof.Compared with the existing inhibitors, the compounds of formula I have...

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Bibliographische Detailangaben
Hauptverfasser: QIAN, Mengfei, YUAN, Haiqing, YIN, Wei, LV, Xiashi, PENG, Cheng, ZOU, Gang, LI, Danbin, HAN, Jian, SHEN, Wei, WU, Zhen Jim, GONG, Chaojun
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure provides the synthesis and application of respiratory syncytial virus inhibitor, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer, solvate, prodrug or isotope label thereof.Compared with the existing inhibitors, the compounds of formula I have the advantages of superior activity and higher exposure in vivo.