METHOD COMBINING TARGETED RNA OR C-DNA IN VITRO SEQUENCING USING PADLOCK OLIGONUCLEOTIDES COMPRISING A SPATIAL UNIQUE MOLECULAR IDENTIFIER (SUMI) AND IN SITU SEQUENCING

Microscopy imaging that allow for multiple mRNAs, proteins and metabolites to be spatially resolved at a subcellular level provides valuable molecular information which is a crucial factor for understanding tissue heterogeneity as for example within the tumor micro environment. The current invention...

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Hauptverfasser:	SPIECKER, Heinrich, NEHME, Chris, NEIL, Emily, ROTHMANN, Thomas, HOSONO, Seiyu, MEYER, Hansueli, PINARD, Robert, HINDMAN, Ryan, BOSIO, Andreas
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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