ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN ROR1, AND USE FOR THE SAME
The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of...
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| creator | KIM, Sung Min YANG, Young-Jae PARK, Kyungjin KIM, Hyoung Rae YEOM, Donghoon BAEK, Ju Yuel PARK, Minji RYU, Hyun Min CHAE, Jeiwook SONG, Daehae SUNG, Byungje JUNG, Jinwon LEE, Yangsoon KANG, Dae Hyuck HAN, Nara PARK, Yun Hee LEE, Chang Sun YOU, Ji-Na LEE, Bora EOM, Jaehyun AHN, Jinhyung PARK, Kyung Eun KIM, Yong Zu YOO, Jiseon KIM. Juhee HONG, Youngeun OH, Ji Hye LEE, Ju Young LEE, Hyeun Joung SONG, Ho Young |
| description | The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same. |
| format | Patent |
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Juhee ; HONG, Youngeun ; OH, Ji Hye ; LEE, Ju Young ; LEE, Hyeun Joung ; SONG, Ho Young</creator><creatorcontrib>KIM, Sung Min ; YANG, Young-Jae ; PARK, Kyungjin ; KIM, Hyoung Rae ; YEOM, Donghoon ; BAEK, Ju Yuel ; PARK, Minji ; RYU, Hyun Min ; CHAE, Jeiwook ; SONG, Daehae ; SUNG, Byungje ; JUNG, Jinwon ; LEE, Yangsoon ; KANG, Dae Hyuck ; HAN, Nara ; PARK, Yun Hee ; LEE, Chang Sun ; YOU, Ji-Na ; LEE, Bora ; EOM, Jaehyun ; AHN, Jinhyung ; PARK, Kyung Eun ; KIM, Yong Zu ; YOO, Jiseon ; KIM. Juhee ; HONG, Youngeun ; OH, Ji Hye ; LEE, Ju Young ; LEE, Hyeun Joung ; SONG, Ho Young</creatorcontrib><description>The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220713&DB=EPODOC&CC=EP&NR=4025257A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220713&DB=EPODOC&CC=EP&NR=4025257A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, Sung Min</creatorcontrib><creatorcontrib>YANG, Young-Jae</creatorcontrib><creatorcontrib>PARK, Kyungjin</creatorcontrib><creatorcontrib>KIM, Hyoung Rae</creatorcontrib><creatorcontrib>YEOM, Donghoon</creatorcontrib><creatorcontrib>BAEK, Ju Yuel</creatorcontrib><creatorcontrib>PARK, Minji</creatorcontrib><creatorcontrib>RYU, Hyun Min</creatorcontrib><creatorcontrib>CHAE, Jeiwook</creatorcontrib><creatorcontrib>SONG, Daehae</creatorcontrib><creatorcontrib>SUNG, Byungje</creatorcontrib><creatorcontrib>JUNG, Jinwon</creatorcontrib><creatorcontrib>LEE, Yangsoon</creatorcontrib><creatorcontrib>KANG, Dae Hyuck</creatorcontrib><creatorcontrib>HAN, Nara</creatorcontrib><creatorcontrib>PARK, Yun Hee</creatorcontrib><creatorcontrib>LEE, Chang Sun</creatorcontrib><creatorcontrib>YOU, Ji-Na</creatorcontrib><creatorcontrib>LEE, Bora</creatorcontrib><creatorcontrib>EOM, Jaehyun</creatorcontrib><creatorcontrib>AHN, Jinhyung</creatorcontrib><creatorcontrib>PARK, Kyung Eun</creatorcontrib><creatorcontrib>KIM, Yong Zu</creatorcontrib><creatorcontrib>YOO, Jiseon</creatorcontrib><creatorcontrib>KIM. 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Juhee</au><au>HONG, Youngeun</au><au>OH, Ji Hye</au><au>LEE, Ju Young</au><au>LEE, Hyeun Joung</au><au>SONG, Ho Young</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN ROR1, AND USE FOR THE SAME</title><date>2022-07-13</date><risdate>2022</risdate><abstract>The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN ROR1, AND USE FOR THE SAME |
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