PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR

Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YU, Jianxin, GE, Hui, ZHANG, Zhihui, XIA, Guangxin, SHU, Sijie, ZHANG, Bingbin, SHI, Chen, KE, Ying, LIU, Yanjun, LOU, Jiangsong, HUO, Guoyong, WANG, Qian, MAO, Yu, ZHANG, Chi, ZHANG, Lin
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator YU, Jianxin
GE, Hui
ZHANG, Zhihui
XIA, Guangxin
SHU, Sijie
ZHANG, Bingbin
SHI, Chen
KE, Ying
LIU, Yanjun
LOU, Jiangsong
HUO, Guoyong
WANG, Qian
MAO, Yu
ZHANG, Chi
ZHANG, Lin
description Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4008719A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4008719A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4008719A23</originalsourceid><addsrcrecordid>eNrjZPAOiAxyjPL38fdzVXD0c1EAcj19PV08gVxnf98A_1A_Fx2IRJBrgGOQY4inv5-Cr2uIh78LWDg02FUhxMM1yNXNP4iHgTUtMac4lRdKczMouLmGOHvophbkx6cWFyQmp-allsS7BpgYGFiYG1o6GhkToQQARuwtXw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR</title><source>esp@cenet</source><creator>YU, Jianxin ; GE, Hui ; ZHANG, Zhihui ; XIA, Guangxin ; SHU, Sijie ; ZHANG, Bingbin ; SHI, Chen ; KE, Ying ; LIU, Yanjun ; LOU, Jiangsong ; HUO, Guoyong ; WANG, Qian ; MAO, Yu ; ZHANG, Chi ; ZHANG, Lin</creator><creatorcontrib>YU, Jianxin ; GE, Hui ; ZHANG, Zhihui ; XIA, Guangxin ; SHU, Sijie ; ZHANG, Bingbin ; SHI, Chen ; KE, Ying ; LIU, Yanjun ; LOU, Jiangsong ; HUO, Guoyong ; WANG, Qian ; MAO, Yu ; ZHANG, Chi ; ZHANG, Lin</creatorcontrib><description>Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220608&amp;DB=EPODOC&amp;CC=EP&amp;NR=4008719A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220608&amp;DB=EPODOC&amp;CC=EP&amp;NR=4008719A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YU, Jianxin</creatorcontrib><creatorcontrib>GE, Hui</creatorcontrib><creatorcontrib>ZHANG, Zhihui</creatorcontrib><creatorcontrib>XIA, Guangxin</creatorcontrib><creatorcontrib>SHU, Sijie</creatorcontrib><creatorcontrib>ZHANG, Bingbin</creatorcontrib><creatorcontrib>SHI, Chen</creatorcontrib><creatorcontrib>KE, Ying</creatorcontrib><creatorcontrib>LIU, Yanjun</creatorcontrib><creatorcontrib>LOU, Jiangsong</creatorcontrib><creatorcontrib>HUO, Guoyong</creatorcontrib><creatorcontrib>WANG, Qian</creatorcontrib><creatorcontrib>MAO, Yu</creatorcontrib><creatorcontrib>ZHANG, Chi</creatorcontrib><creatorcontrib>ZHANG, Lin</creatorcontrib><title>PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR</title><description>Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAOiAxyjPL38fdzVXD0c1EAcj19PV08gVxnf98A_1A_Fx2IRJBrgGOQY4inv5-Cr2uIh78LWDg02FUhxMM1yNXNP4iHgTUtMac4lRdKczMouLmGOHvophbkx6cWFyQmp-allsS7BpgYGFiYG1o6GhkToQQARuwtXw</recordid><startdate>20220608</startdate><enddate>20220608</enddate><creator>YU, Jianxin</creator><creator>GE, Hui</creator><creator>ZHANG, Zhihui</creator><creator>XIA, Guangxin</creator><creator>SHU, Sijie</creator><creator>ZHANG, Bingbin</creator><creator>SHI, Chen</creator><creator>KE, Ying</creator><creator>LIU, Yanjun</creator><creator>LOU, Jiangsong</creator><creator>HUO, Guoyong</creator><creator>WANG, Qian</creator><creator>MAO, Yu</creator><creator>ZHANG, Chi</creator><creator>ZHANG, Lin</creator><scope>EVB</scope></search><sort><creationdate>20220608</creationdate><title>PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR</title><author>YU, Jianxin ; GE, Hui ; ZHANG, Zhihui ; XIA, Guangxin ; SHU, Sijie ; ZHANG, Bingbin ; SHI, Chen ; KE, Ying ; LIU, Yanjun ; LOU, Jiangsong ; HUO, Guoyong ; WANG, Qian ; MAO, Yu ; ZHANG, Chi ; ZHANG, Lin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4008719A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>YU, Jianxin</creatorcontrib><creatorcontrib>GE, Hui</creatorcontrib><creatorcontrib>ZHANG, Zhihui</creatorcontrib><creatorcontrib>XIA, Guangxin</creatorcontrib><creatorcontrib>SHU, Sijie</creatorcontrib><creatorcontrib>ZHANG, Bingbin</creatorcontrib><creatorcontrib>SHI, Chen</creatorcontrib><creatorcontrib>KE, Ying</creatorcontrib><creatorcontrib>LIU, Yanjun</creatorcontrib><creatorcontrib>LOU, Jiangsong</creatorcontrib><creatorcontrib>HUO, Guoyong</creatorcontrib><creatorcontrib>WANG, Qian</creatorcontrib><creatorcontrib>MAO, Yu</creatorcontrib><creatorcontrib>ZHANG, Chi</creatorcontrib><creatorcontrib>ZHANG, Lin</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YU, Jianxin</au><au>GE, Hui</au><au>ZHANG, Zhihui</au><au>XIA, Guangxin</au><au>SHU, Sijie</au><au>ZHANG, Bingbin</au><au>SHI, Chen</au><au>KE, Ying</au><au>LIU, Yanjun</au><au>LOU, Jiangsong</au><au>HUO, Guoyong</au><au>WANG, Qian</au><au>MAO, Yu</au><au>ZHANG, Chi</au><au>ZHANG, Lin</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR</title><date>2022-06-08</date><risdate>2022</risdate><abstract>Disclosed in the present invention are a pyrazolone and pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone and pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4008719A2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRAZOLONE AND PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T00%3A17%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YU,%20Jianxin&rft.date=2022-06-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4008719A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true