IMPROVED METHOD FOR PREPARING MALEATE SALT OF PARA-SUBSTITUTED CIS-CYCLOHEXYLAMINO NITRILE

Disclosed is an improved method for preparing a maleate salt of cis-para-substituted cyclohexylamino nitrile depicted by formula (I), the method comprising adding maleic acid, at a molar ratio of 0.3 to 0.55, to a solution of para-substituted cis- and trans-cyclohexylamino nitrile compounds correspo...

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Hauptverfasser: LIU, Hailong, GUO, Hongyong, GUO, Qingchun, DONG, Zhipeng, YUAN, Ligang
Format: Patent
Sprache:eng ; fre ; ger
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