SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS

Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions contai...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DORICH, Stéphane, LANOIX, Stéphanie, JONES, Paul, BLACK, Cameron, TRUONG, Vouy Linh, TRUCHON, Jean-François, ABDOLI, Abbas, CRANE, Sheldon N, FADER, Lee, PICARD, Audrey, LACBAY, Cyrus M, ST-ONGE, Miguel
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator DORICH, Stéphane
LANOIX, Stéphanie
JONES, Paul
BLACK, Cameron
TRUONG, Vouy Linh
TRUCHON, Jean-François
ABDOLI, Abbas
CRANE, Sheldon N
FADER, Lee
PICARD, Audrey
LACBAY, Cyrus M
ST-ONGE, Miguel
description Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4003993A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4003993A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4003993A13</originalsourceid><addsrcrecordid>eNrjZHANDnUKDvEMCQ1xdVEw0vX1Dwrw8Pfx9PMPiAzydPH0c1VwcQ3yDHMM8QxzDVZwBKKQIAVvTz_HYFcFTz8PTyfPEP-gYB4G1rTEnOJUXijNzaDg5hri7KGbWpAfn1pckJicmpdaEu8aYGJgYGxpaexoaEyEEgB1xiwt</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS</title><source>esp@cenet</source><creator>DORICH, Stéphane ; LANOIX, Stéphanie ; JONES, Paul ; BLACK, Cameron ; TRUONG, Vouy Linh ; TRUCHON, Jean-François ; ABDOLI, Abbas ; CRANE, Sheldon N ; FADER, Lee ; PICARD, Audrey ; LACBAY, Cyrus M ; ST-ONGE, Miguel</creator><creatorcontrib>DORICH, Stéphane ; LANOIX, Stéphanie ; JONES, Paul ; BLACK, Cameron ; TRUONG, Vouy Linh ; TRUCHON, Jean-François ; ABDOLI, Abbas ; CRANE, Sheldon N ; FADER, Lee ; PICARD, Audrey ; LACBAY, Cyrus M ; ST-ONGE, Miguel</creatorcontrib><description>Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220601&amp;DB=EPODOC&amp;CC=EP&amp;NR=4003993A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220601&amp;DB=EPODOC&amp;CC=EP&amp;NR=4003993A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DORICH, Stéphane</creatorcontrib><creatorcontrib>LANOIX, Stéphanie</creatorcontrib><creatorcontrib>JONES, Paul</creatorcontrib><creatorcontrib>BLACK, Cameron</creatorcontrib><creatorcontrib>TRUONG, Vouy Linh</creatorcontrib><creatorcontrib>TRUCHON, Jean-François</creatorcontrib><creatorcontrib>ABDOLI, Abbas</creatorcontrib><creatorcontrib>CRANE, Sheldon N</creatorcontrib><creatorcontrib>FADER, Lee</creatorcontrib><creatorcontrib>PICARD, Audrey</creatorcontrib><creatorcontrib>LACBAY, Cyrus M</creatorcontrib><creatorcontrib>ST-ONGE, Miguel</creatorcontrib><title>SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS</title><description>Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHANDnUKDvEMCQ1xdVEw0vX1Dwrw8Pfx9PMPiAzydPH0c1VwcQ3yDHMM8QxzDVZwBKKQIAVvTz_HYFcFTz8PTyfPEP-gYB4G1rTEnOJUXijNzaDg5hri7KGbWpAfn1pckJicmpdaEu8aYGJgYGxpaexoaEyEEgB1xiwt</recordid><startdate>20220601</startdate><enddate>20220601</enddate><creator>DORICH, Stéphane</creator><creator>LANOIX, Stéphanie</creator><creator>JONES, Paul</creator><creator>BLACK, Cameron</creator><creator>TRUONG, Vouy Linh</creator><creator>TRUCHON, Jean-François</creator><creator>ABDOLI, Abbas</creator><creator>CRANE, Sheldon N</creator><creator>FADER, Lee</creator><creator>PICARD, Audrey</creator><creator>LACBAY, Cyrus M</creator><creator>ST-ONGE, Miguel</creator><scope>EVB</scope></search><sort><creationdate>20220601</creationdate><title>SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS</title><author>DORICH, Stéphane ; LANOIX, Stéphanie ; JONES, Paul ; BLACK, Cameron ; TRUONG, Vouy Linh ; TRUCHON, Jean-François ; ABDOLI, Abbas ; CRANE, Sheldon N ; FADER, Lee ; PICARD, Audrey ; LACBAY, Cyrus M ; ST-ONGE, Miguel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4003993A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DORICH, Stéphane</creatorcontrib><creatorcontrib>LANOIX, Stéphanie</creatorcontrib><creatorcontrib>JONES, Paul</creatorcontrib><creatorcontrib>BLACK, Cameron</creatorcontrib><creatorcontrib>TRUONG, Vouy Linh</creatorcontrib><creatorcontrib>TRUCHON, Jean-François</creatorcontrib><creatorcontrib>ABDOLI, Abbas</creatorcontrib><creatorcontrib>CRANE, Sheldon N</creatorcontrib><creatorcontrib>FADER, Lee</creatorcontrib><creatorcontrib>PICARD, Audrey</creatorcontrib><creatorcontrib>LACBAY, Cyrus M</creatorcontrib><creatorcontrib>ST-ONGE, Miguel</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DORICH, Stéphane</au><au>LANOIX, Stéphanie</au><au>JONES, Paul</au><au>BLACK, Cameron</au><au>TRUONG, Vouy Linh</au><au>TRUCHON, Jean-François</au><au>ABDOLI, Abbas</au><au>CRANE, Sheldon N</au><au>FADER, Lee</au><au>PICARD, Audrey</au><au>LACBAY, Cyrus M</au><au>ST-ONGE, Miguel</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS</title><date>2022-06-01</date><risdate>2022</risdate><abstract>Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4003993A1
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T22%3A12%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DORICH,%20St%C3%A9phane&rft.date=2022-06-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4003993A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true