CD63 AGONIST-RELATED METHODS AND COMPOSITIONS

Provided are methods of treating cell proliferative disorders. In some embodiments, the methods include administering to a subject having a cell proliferative disorder a therapeutically effective amount of a CD63 agonist, where the CD63 agonist is administered to the subject to enhance a T cell response to abnormally proliferating cells of the cell proliferative disorder. In certain embodiments, the methods include administering to a subject having a cell proliferative disorder a therapeutically effective amount of a CD63 agonist and a therapeutically effective amount of a T cell activator. Also provided are pharmaceutical compositions and kits that find use, e.g., in practicing the methods.