MODIFIED AAV CAPSID PROTEINS FOR TREATMENT OF ARTHRITIC DISEASE

The invention relates to recombinant adeno-associated virus (rAAV) virions for gene therapy, wherein the rAAV virions comprise a novel capsid protein. In particular, the invention relates to the use of such virions in gene therapy for the treatment of an arthritic disease, such as for example rheuma...

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Hauptverfasser: GRIMM, Dirk, VAN DER SANDEN, Sabine Maria Gertrude, SNOEK, Susanne Anna, BROEKSTRA, Niels, FINN, Jonathan Douglas, BÖRNER, Kathleen
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creator GRIMM, Dirk
VAN DER SANDEN, Sabine Maria Gertrude
SNOEK, Susanne Anna
BROEKSTRA, Niels
FINN, Jonathan Douglas
BÖRNER, Kathleen
description The invention relates to recombinant adeno-associated virus (rAAV) virions for gene therapy, wherein the rAAV virions comprise a novel capsid protein. In particular, the invention relates to the use of such virions in gene therapy for the treatment of an arthritic disease, such as for example rheumatoid arthritis, or symptoms thereof, preferably by intraarticular administration.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title MODIFIED AAV CAPSID PROTEINS FOR TREATMENT OF ARTHRITIC DISEASE
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