CD38-BINDING AGENTS AND USES THEREOF

Among other things, the present disclosure provides compounds comprising antibody binding moieties and CD38-binding targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells....

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Hauptverfasser: BERBASOVA, Tetyana, WELSCH, Matthew Ernest, BUNIN, Anna, RASTELLI, Luca, ROSSI, Ann Marie K
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creator BERBASOVA, Tetyana
WELSCH, Matthew Ernest
BUNIN, Anna
RASTELLI, Luca
ROSSI, Ann Marie K
description Among other things, the present disclosure provides compounds comprising antibody binding moieties and CD38-binding targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells. Provided technologies are useful for treating various diseases including cancer.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title CD38-BINDING AGENTS AND USES THEREOF
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