BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF
The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the a...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | PARK, Kyungjin KIM, Dongin SUNG, Byungje SONG, Daehae YUN, Hyesu SON, Yong-Gyu JUNG, Jinwon AN, Sungwon KIM, Juhee LEE, Bora EOM, Jaehyun AHN, Jinhyung |
| description | The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3985022A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3985022A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3985022A13</originalsourceid><addsrcrecordid>eNrjZDB38gwOcHX2dPN0VnD0C_F08neJVHB0d_T0Cw5RSNQNjvTT93R3MwwCSroohAa7KoR4uAa5-rvxMLCmJeYUp_JCaW4GBTfXEGcP3dSC_PjU4oLE5NS81JJ41wBjSwtTAyMjR0NjIpQAANU4J48</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF</title><source>esp@cenet</source><creator>PARK, Kyungjin ; KIM, Dongin ; SUNG, Byungje ; SONG, Daehae ; YUN, Hyesu ; SON, Yong-Gyu ; JUNG, Jinwon ; AN, Sungwon ; KIM, Juhee ; LEE, Bora ; EOM, Jaehyun ; AHN, Jinhyung</creator><creatorcontrib>PARK, Kyungjin ; KIM, Dongin ; SUNG, Byungje ; SONG, Daehae ; YUN, Hyesu ; SON, Yong-Gyu ; JUNG, Jinwon ; AN, Sungwon ; KIM, Juhee ; LEE, Bora ; EOM, Jaehyun ; AHN, Jinhyung</creatorcontrib><description>The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220420&DB=EPODOC&CC=EP&NR=3985022A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220420&DB=EPODOC&CC=EP&NR=3985022A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PARK, Kyungjin</creatorcontrib><creatorcontrib>KIM, Dongin</creatorcontrib><creatorcontrib>SUNG, Byungje</creatorcontrib><creatorcontrib>SONG, Daehae</creatorcontrib><creatorcontrib>YUN, Hyesu</creatorcontrib><creatorcontrib>SON, Yong-Gyu</creatorcontrib><creatorcontrib>JUNG, Jinwon</creatorcontrib><creatorcontrib>AN, Sungwon</creatorcontrib><creatorcontrib>KIM, Juhee</creatorcontrib><creatorcontrib>LEE, Bora</creatorcontrib><creatorcontrib>EOM, Jaehyun</creatorcontrib><creatorcontrib>AHN, Jinhyung</creatorcontrib><title>BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF</title><description>The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB38gwOcHX2dPN0VnD0C_F08neJVHB0d_T0Cw5RSNQNjvTT93R3MwwCSroohAa7KoR4uAa5-rvxMLCmJeYUp_JCaW4GBTfXEGcP3dSC_PjU4oLE5NS81JJ41wBjSwtTAyMjR0NjIpQAANU4J48</recordid><startdate>20220420</startdate><enddate>20220420</enddate><creator>PARK, Kyungjin</creator><creator>KIM, Dongin</creator><creator>SUNG, Byungje</creator><creator>SONG, Daehae</creator><creator>YUN, Hyesu</creator><creator>SON, Yong-Gyu</creator><creator>JUNG, Jinwon</creator><creator>AN, Sungwon</creator><creator>KIM, Juhee</creator><creator>LEE, Bora</creator><creator>EOM, Jaehyun</creator><creator>AHN, Jinhyung</creator><scope>EVB</scope></search><sort><creationdate>20220420</creationdate><title>BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF</title><author>PARK, Kyungjin ; KIM, Dongin ; SUNG, Byungje ; SONG, Daehae ; YUN, Hyesu ; SON, Yong-Gyu ; JUNG, Jinwon ; AN, Sungwon ; KIM, Juhee ; LEE, Bora ; EOM, Jaehyun ; AHN, Jinhyung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3985022A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PARK, Kyungjin</creatorcontrib><creatorcontrib>KIM, Dongin</creatorcontrib><creatorcontrib>SUNG, Byungje</creatorcontrib><creatorcontrib>SONG, Daehae</creatorcontrib><creatorcontrib>YUN, Hyesu</creatorcontrib><creatorcontrib>SON, Yong-Gyu</creatorcontrib><creatorcontrib>JUNG, Jinwon</creatorcontrib><creatorcontrib>AN, Sungwon</creatorcontrib><creatorcontrib>KIM, Juhee</creatorcontrib><creatorcontrib>LEE, Bora</creatorcontrib><creatorcontrib>EOM, Jaehyun</creatorcontrib><creatorcontrib>AHN, Jinhyung</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PARK, Kyungjin</au><au>KIM, Dongin</au><au>SUNG, Byungje</au><au>SONG, Daehae</au><au>YUN, Hyesu</au><au>SON, Yong-Gyu</au><au>JUNG, Jinwon</au><au>AN, Sungwon</au><au>KIM, Juhee</au><au>LEE, Bora</au><au>EOM, Jaehyun</au><au>AHN, Jinhyung</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF</title><date>2022-04-20</date><risdate>2022</risdate><abstract>The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3985022A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BISPECIFIC ANTIBODY AGAINST a-SYN/IGF1R AND USE THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T13%3A04%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PARK,%20Kyungjin&rft.date=2022-04-20&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3985022A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |