METHODS AND REAGENTS FOR DIAGNOSIS OF SARS-COV-2 INFECTION

The present invention relates to a method for diagnosing a SARS-CoV-2 infection comprising the step of detecting the presence or absence of an antibody to SEQ ID NO: 1, preferably IgA class antibody, in a sample from a subject, a method for the differential diagnosis of a coronavirus infection, a us...

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Hauptverfasser: Lindhorst, Fabian, Stiba, Konstanze, Müller, Marcel, Corman, Victor, Lattwein, Erik, Steinhagen, Katja, Messing, Claudia, Neugebauer, Eva
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creator Lindhorst, Fabian
Stiba, Konstanze
Müller, Marcel
Corman, Victor
Lattwein, Erik
Steinhagen, Katja
Messing, Claudia
Neugebauer, Eva
description The present invention relates to a method for diagnosing a SARS-CoV-2 infection comprising the step of detecting the presence or absence of an antibody to SEQ ID NO: 1, preferably IgA class antibody, in a sample from a subject, a method for the differential diagnosis of a coronavirus infection, a use of an antibody to SEQ ID NO: 1, preferably IgA class antibody for diagnosing a SARS-CoV-2 infection or for the differential diagnosis of a coronavirus infection, preferably for distinguishing between a SARS-CoV-2, MERS and NL63, 229E, OC43 and HKU1 infection, and a kit comprising a polypeptide comprising SEQ ID NO: 1 or a variant thereof, preferably coated to a diagnostically useful carrier and one or more, preferably all reagents from the group comprising an antibody to SEQ ID NO: 1, a washing buffer, a means for detecting the presence of an antibody, preferably IgA class antibody, preferably a secondary antibody binding specifically to IgA class antibodies, preferably comprising a detectable label, and a dilution buffer.
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subjects CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
title METHODS AND REAGENTS FOR DIAGNOSIS OF SARS-COV-2 INFECTION
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