COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTION

COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTION

Described are RNA interference (RNAi) agents for inhibiting the expression of Hepatitis B Virus (HBV) used in combination with a capsid assembly modulator (CAM) and methods of administering same. The HBV RNAi agents and CAMs are administered in ratios to effectively inhibit HBV gene expression and t...

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Hauptverfasser: SNOEYS, Jan, SIMMEN, Kenneth Alan, KALMEIJER, Ronald Cornelis Marie, BIERMER, Michael, BEUMONT, Maria Gloria, LENZ, Oliver
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator SNOEYS, Jan
SIMMEN, Kenneth Alan
KALMEIJER, Ronald Cornelis Marie
BIERMER, Michael
BEUMONT, Maria Gloria
LENZ, Oliver
description Described are RNA interference (RNAi) agents for inhibiting the expression of Hepatitis B Virus (HBV) used in combination with a capsid assembly modulator (CAM) and methods of administering same. The HBV RNAi agents and CAMs are administered in ratios to effectively inhibit HBV gene expression and to treat diseases and conditions associated with HBV infection.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTION
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