WEE1 INHIBITOR AND PREPARATION AND USE THEREOF

The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula 11, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provid...

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Hauptverfasser: CHEN, Changjun, ZHANG, Jiuqing, LI, Jijun, HE, Weinan, YAN, Qin, ZHANG, Xiaojun, WANG, Yeliu, SHANG, Xianxing, LI, Hongjuan, HOU, Deng, YAO, Jinsuo, SUN, Yinghui, LU, Chang, ZHU, Yan, LIU, Qichao
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creator CHEN, Changjun
ZHANG, Jiuqing
LI, Jijun
HE, Weinan
YAN, Qin
ZHANG, Xiaojun
WANG, Yeliu
SHANG, Xianxing
LI, Hongjuan
HOU, Deng
YAO, Jinsuo
SUN, Yinghui
LU, Chang
ZHU, Yan
LIU, Qichao
description The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula 11, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provides use of the WEE1 inhibitor in the manufacture of a medicament for the treatment of a disease associated with WEE1 activity. The WEE1 inhibitor provided by the present invention can effectively treat the disease associated with WEE1 activity.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title WEE1 INHIBITOR AND PREPARATION AND USE THEREOF
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