NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF
The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | GUO, Zufeng AHMADI, Ali LIU, Jun O PENG, Hanjing SUN, Zhaoli QI, Le WANG, Yuefan PEIFFER, Brandon J |
| description | The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3914599A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3914599A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3914599A43</originalsourceid><addsrcrecordid>eNrjZDD28_fT9fT1DfXzDw4NCAhyDQ72DHNVcPM2NTBTcPRz9PF3DwbSLgqhwa4KIR6uQa7-bjwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDE5NS-1JN41wNjS0MTU0tLRxJgIJQBc2SbM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF</title><source>esp@cenet</source><creator>GUO, Zufeng ; AHMADI, Ali ; LIU, Jun O ; PENG, Hanjing ; SUN, Zhaoli ; QI, Le ; WANG, Yuefan ; PEIFFER, Brandon J</creator><creatorcontrib>GUO, Zufeng ; AHMADI, Ali ; LIU, Jun O ; PENG, Hanjing ; SUN, Zhaoli ; QI, Le ; WANG, Yuefan ; PEIFFER, Brandon J</creatorcontrib><description>The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221019&DB=EPODOC&CC=EP&NR=3914599A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221019&DB=EPODOC&CC=EP&NR=3914599A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GUO, Zufeng</creatorcontrib><creatorcontrib>AHMADI, Ali</creatorcontrib><creatorcontrib>LIU, Jun O</creatorcontrib><creatorcontrib>PENG, Hanjing</creatorcontrib><creatorcontrib>SUN, Zhaoli</creatorcontrib><creatorcontrib>QI, Le</creatorcontrib><creatorcontrib>WANG, Yuefan</creatorcontrib><creatorcontrib>PEIFFER, Brandon J</creatorcontrib><title>NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF</title><description>The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD28_fT9fT1DfXzDw4NCAhyDQ72DHNVcPM2NTBTcPRz9PF3DwbSLgqhwa4KIR6uQa7-bjwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDE5NS-1JN41wNjS0MTU0tLRxJgIJQBc2SbM</recordid><startdate>20221019</startdate><enddate>20221019</enddate><creator>GUO, Zufeng</creator><creator>AHMADI, Ali</creator><creator>LIU, Jun O</creator><creator>PENG, Hanjing</creator><creator>SUN, Zhaoli</creator><creator>QI, Le</creator><creator>WANG, Yuefan</creator><creator>PEIFFER, Brandon J</creator><scope>EVB</scope></search><sort><creationdate>20221019</creationdate><title>NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF</title><author>GUO, Zufeng ; AHMADI, Ali ; LIU, Jun O ; PENG, Hanjing ; SUN, Zhaoli ; QI, Le ; WANG, Yuefan ; PEIFFER, Brandon J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3914599A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>GUO, Zufeng</creatorcontrib><creatorcontrib>AHMADI, Ali</creatorcontrib><creatorcontrib>LIU, Jun O</creatorcontrib><creatorcontrib>PENG, Hanjing</creatorcontrib><creatorcontrib>SUN, Zhaoli</creatorcontrib><creatorcontrib>QI, Le</creatorcontrib><creatorcontrib>WANG, Yuefan</creatorcontrib><creatorcontrib>PEIFFER, Brandon J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GUO, Zufeng</au><au>AHMADI, Ali</au><au>LIU, Jun O</au><au>PENG, Hanjing</au><au>SUN, Zhaoli</au><au>QI, Le</au><au>WANG, Yuefan</au><au>PEIFFER, Brandon J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF</title><date>2022-10-19</date><risdate>2022</risdate><abstract>The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3914599A4 |
| source | esp@cenet |
| subjects | CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T05%3A57%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GUO,%20Zufeng&rft.date=2022-10-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3914599A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |