HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS

The present invention relates to chemical compounds having a general formula (I), as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. T...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	LI, Kexue, BANERJEE, Abhisek, FROHN, Michael J, JIA, Lei, XUE, Qiufen May, KALLER, Matthew Richard, NGUYEN, Thomas T, CHEN, Jian Jeffrey, BOURBEAU, Matthew Paul, NISHIMURA, Nobuko, ALLEN, John Gordon, TAMAYO, Nuria A
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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