MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A DEVICE

Method embodiments for performing a structured collection protocol by utilizing a collection device comprise collecting one or more sampling sets of biomarker data, wherein each sampling set comprises a sufficient plurality of sampling instances recorded over a collection period. The methods further include determining compliance with adherence criteria for the sampling instances, wherein noncompliance with adherence criteria is recorded as an adherence event, classifying sampling instances as primary samples or secondary samples, wherein primary samples, which do not have corresponding recorded adherence events, are sampling instances utilized in the calculations performed by the processor that yield therapy results for a diabetic person, and secondary samples are sampling instances not utilized in the calculations, unless one or more secondary samples are promoted to primary samples, and performing at least one additional task if one or more sampling instances is a primary sample with a corresponding recorded adherence event.