FORMULATIONS, METHODS, KIT, AND DOSAGE FORMS FOR IMPROVED STABILITY OF AN ACTIVE PHARMACEUTICAL INGREDIENT

Embodiments of the disclosure relate generally to formulations, methods, kits, and dosage forms for improved topical pharmaceutical formulation comprising an active ingredient, wherein the active ingredient comprises a compound selected from the group consisting of the Formula (I), Formula (II), and...

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Bibliographische Detailangaben
Hauptverfasser: AUDETT, Jay, RAO, Niranjan, THOMPSON, Scott K, GOSWAMI, Tarum, SACHDEVA, Sameer, BANSAL, Padam, JIMENEZ, Pablo
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Embodiments of the disclosure relate generally to formulations, methods, kits, and dosage forms for improved topical pharmaceutical formulation comprising an active ingredient, wherein the active ingredient comprises a compound selected from the group consisting of the Formula (I), Formula (II), and Formula (III): The formulations can further comprise a hydrophilic non-ionic surfactant comprising a poloxamer. These formulations are useful in treating inflammation, pruritus and/or pain, or for treating conditions for which the signs and symptoms include inflammation, pruritis and/or pain, by topical administration to a subject.