MODIFIED CLOSED-ENDED DNA (CEDNA) COMPRISING SYMMETRICAL MODIFIED INVERTED TERMINAL REPEATS

Described herein are ceDNA vectors having linear and continuous structure can be produced in high yields and used for effective transfer and expression of a transgene. According to some embodiments, ceDNA vectors comprise at least one heterologous nucleotide sequence operably positioned between two...

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Bibliographische Detailangaben
Hauptverfasser: ALKAN, Ozan, KOTIN, Robert Michael, JONES, Annaliese
Format: Patent
Sprache:eng ; fre ; ger
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