NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.

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Hauptverfasser: SAMSONOV, Mikhail Vasilievich, MOLOKOEDOV, Aleksandr Sergeevich, KAZAKOVA, Olga Alekseevna, KHAPCHAEV, Asker Yusufovich, AZMUKO, Andrey Andreevich, OVCHINNIKOV, Mihail Vladimirovich, SHIRINSKY, Vladimir Pavlovich, ARZAMASCEV, Yevgeniy Veniaminovich, BUSHUEV, Valeri Nikolaevich, TEREKHOVA, Olga Alexandrovna, PALKEEVA, Marina Yevgenievna, SIDOROVA, Mariya Vladimirovna
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creator SAMSONOV, Mikhail Vasilievich
MOLOKOEDOV, Aleksandr Sergeevich
KAZAKOVA, Olga Alekseevna
KHAPCHAEV, Asker Yusufovich
AZMUKO, Andrey Andreevich
OVCHINNIKOV, Mihail Vladimirovich
SHIRINSKY, Vladimir Pavlovich
ARZAMASCEV, Yevgeniy Veniaminovich
BUSHUEV, Valeri Nikolaevich
TEREKHOVA, Olga Alexandrovna
PALKEEVA, Marina Yevgenievna
SIDOROVA, Mariya Vladimirovna
description The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM
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