NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF
The present invention discloses a novel pharmaceutical composition of lapatinib or a pharmaceutically acceptable salt thereof preferably oral solid dosage form of a tablet with pharmaceutically acceptable excipients and method of preparation thereof. The pharmaceutical composition of present inventi...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SHARMA, Mukeshkumar Subhashchandra PATEL, Prashant Karamshibhai PATEL, Harikrishnabhai Vinubhai TRIVEDI, Madhavkumar Dilipbhai GANDHI, Prashant Kanaiyalal BADIGER, Aravind Manappa PANCHAL, Nimitkumar Harishchandra SHAH, Dharmesh Mahendrabhai |
| description | The present invention discloses a novel pharmaceutical composition of lapatinib or a pharmaceutically acceptable salt thereof preferably oral solid dosage form of a tablet with pharmaceutically acceptable excipients and method of preparation thereof. The pharmaceutical composition of present invention comprises lapatinib ditosylate monohydrate with one or more pharmaceutically acceptable excipients selected from the group comprising of at least one diluent, at least one disintegrant, at least one binder, at least one lubricant, wherein the composition does not comprise microcrystalline cellulose and sodium starch glycolate. The pharmaceutical composition according to the present invention is economical and advanced dosage form over existing dosage form, with less side effects and time efficient, especially for large scale production, whereby the pharmaceutical composition shows a desired dissolution profile and higher stability with minimum use of excipients. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3846787A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3846787A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3846787A13</originalsourceid><addsrcrecordid>eNqNykEKwjAQQNFsXIh6h7mAC6nYbsdk0gSSTEjTroRSJK5EC_X-SMEDuPp8eFtxCzyQA8k-cmez5QCswWHEbIO9rsMJHXTsrALFHbYEmpMHDAo8ZcNqRR5Dr1HmPtnQQjaUiPVebB7TcymHX3cCNGVpjmV-j2WZp3t5lc9IsWrOl7qp8VT9Qb46WTHR</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF</title><source>esp@cenet</source><creator>SHARMA, Mukeshkumar Subhashchandra ; PATEL, Prashant Karamshibhai ; PATEL, Harikrishnabhai Vinubhai ; TRIVEDI, Madhavkumar Dilipbhai ; GANDHI, Prashant Kanaiyalal ; BADIGER, Aravind Manappa ; PANCHAL, Nimitkumar Harishchandra ; SHAH, Dharmesh Mahendrabhai</creator><creatorcontrib>SHARMA, Mukeshkumar Subhashchandra ; PATEL, Prashant Karamshibhai ; PATEL, Harikrishnabhai Vinubhai ; TRIVEDI, Madhavkumar Dilipbhai ; GANDHI, Prashant Kanaiyalal ; BADIGER, Aravind Manappa ; PANCHAL, Nimitkumar Harishchandra ; SHAH, Dharmesh Mahendrabhai</creatorcontrib><description>The present invention discloses a novel pharmaceutical composition of lapatinib or a pharmaceutically acceptable salt thereof preferably oral solid dosage form of a tablet with pharmaceutically acceptable excipients and method of preparation thereof. The pharmaceutical composition of present invention comprises lapatinib ditosylate monohydrate with one or more pharmaceutically acceptable excipients selected from the group comprising of at least one diluent, at least one disintegrant, at least one binder, at least one lubricant, wherein the composition does not comprise microcrystalline cellulose and sodium starch glycolate. The pharmaceutical composition according to the present invention is economical and advanced dosage form over existing dosage form, with less side effects and time efficient, especially for large scale production, whereby the pharmaceutical composition shows a desired dissolution profile and higher stability with minimum use of excipients.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210714&DB=EPODOC&CC=EP&NR=3846787A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210714&DB=EPODOC&CC=EP&NR=3846787A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHARMA, Mukeshkumar Subhashchandra</creatorcontrib><creatorcontrib>PATEL, Prashant Karamshibhai</creatorcontrib><creatorcontrib>PATEL, Harikrishnabhai Vinubhai</creatorcontrib><creatorcontrib>TRIVEDI, Madhavkumar Dilipbhai</creatorcontrib><creatorcontrib>GANDHI, Prashant Kanaiyalal</creatorcontrib><creatorcontrib>BADIGER, Aravind Manappa</creatorcontrib><creatorcontrib>PANCHAL, Nimitkumar Harishchandra</creatorcontrib><creatorcontrib>SHAH, Dharmesh Mahendrabhai</creatorcontrib><title>NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF</title><description>The present invention discloses a novel pharmaceutical composition of lapatinib or a pharmaceutically acceptable salt thereof preferably oral solid dosage form of a tablet with pharmaceutically acceptable excipients and method of preparation thereof. The pharmaceutical composition of present invention comprises lapatinib ditosylate monohydrate with one or more pharmaceutically acceptable excipients selected from the group comprising of at least one diluent, at least one disintegrant, at least one binder, at least one lubricant, wherein the composition does not comprise microcrystalline cellulose and sodium starch glycolate. The pharmaceutical composition according to the present invention is economical and advanced dosage form over existing dosage form, with less side effects and time efficient, especially for large scale production, whereby the pharmaceutical composition shows a desired dissolution profile and higher stability with minimum use of excipients.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNykEKwjAQQNFsXIh6h7mAC6nYbsdk0gSSTEjTroRSJK5EC_X-SMEDuPp8eFtxCzyQA8k-cmez5QCswWHEbIO9rsMJHXTsrALFHbYEmpMHDAo8ZcNqRR5Dr1HmPtnQQjaUiPVebB7TcymHX3cCNGVpjmV-j2WZp3t5lc9IsWrOl7qp8VT9Qb46WTHR</recordid><startdate>20210714</startdate><enddate>20210714</enddate><creator>SHARMA, Mukeshkumar Subhashchandra</creator><creator>PATEL, Prashant Karamshibhai</creator><creator>PATEL, Harikrishnabhai Vinubhai</creator><creator>TRIVEDI, Madhavkumar Dilipbhai</creator><creator>GANDHI, Prashant Kanaiyalal</creator><creator>BADIGER, Aravind Manappa</creator><creator>PANCHAL, Nimitkumar Harishchandra</creator><creator>SHAH, Dharmesh Mahendrabhai</creator><scope>EVB</scope></search><sort><creationdate>20210714</creationdate><title>NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF</title><author>SHARMA, Mukeshkumar Subhashchandra ; PATEL, Prashant Karamshibhai ; PATEL, Harikrishnabhai Vinubhai ; TRIVEDI, Madhavkumar Dilipbhai ; GANDHI, Prashant Kanaiyalal ; BADIGER, Aravind Manappa ; PANCHAL, Nimitkumar Harishchandra ; SHAH, Dharmesh Mahendrabhai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3846787A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SHARMA, Mukeshkumar Subhashchandra</creatorcontrib><creatorcontrib>PATEL, Prashant Karamshibhai</creatorcontrib><creatorcontrib>PATEL, Harikrishnabhai Vinubhai</creatorcontrib><creatorcontrib>TRIVEDI, Madhavkumar Dilipbhai</creatorcontrib><creatorcontrib>GANDHI, Prashant Kanaiyalal</creatorcontrib><creatorcontrib>BADIGER, Aravind Manappa</creatorcontrib><creatorcontrib>PANCHAL, Nimitkumar Harishchandra</creatorcontrib><creatorcontrib>SHAH, Dharmesh Mahendrabhai</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHARMA, Mukeshkumar Subhashchandra</au><au>PATEL, Prashant Karamshibhai</au><au>PATEL, Harikrishnabhai Vinubhai</au><au>TRIVEDI, Madhavkumar Dilipbhai</au><au>GANDHI, Prashant Kanaiyalal</au><au>BADIGER, Aravind Manappa</au><au>PANCHAL, Nimitkumar Harishchandra</au><au>SHAH, Dharmesh Mahendrabhai</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF</title><date>2021-07-14</date><risdate>2021</risdate><abstract>The present invention discloses a novel pharmaceutical composition of lapatinib or a pharmaceutically acceptable salt thereof preferably oral solid dosage form of a tablet with pharmaceutically acceptable excipients and method of preparation thereof. The pharmaceutical composition of present invention comprises lapatinib ditosylate monohydrate with one or more pharmaceutically acceptable excipients selected from the group comprising of at least one diluent, at least one disintegrant, at least one binder, at least one lubricant, wherein the composition does not comprise microcrystalline cellulose and sodium starch glycolate. The pharmaceutical composition according to the present invention is economical and advanced dosage form over existing dosage form, with less side effects and time efficient, especially for large scale production, whereby the pharmaceutical composition shows a desired dissolution profile and higher stability with minimum use of excipients.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3846787A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | NOVEL COMPOSITION OF LAPATINIB OF ORAL SOLID DOSAGE FORM AND METHOD OF MANUFACTURING THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T05%3A59%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHARMA,%20Mukeshkumar%20Subhashchandra&rft.date=2021-07-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3846787A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |