REAGENTS BASED ON A TERTIARY AMINE BACKBONE TO INTRODUCE CHEMICAL FUNCTIONALITY IN NUCLEIC ACIDS AND SEQUENCE-CONTROLLED POLYMERS

It is provided an achiral, non-nucleosidic backbone for phosphoramidites that can be inserted with high yields in nucleic acid strands and sequence-controlled oligo(phosphodiester)s through solid phase synthesis (SPS) using a DNA synthesizer. From this backbone, platforms with useful chemical handle...

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Bibliographische Detailangaben
Hauptverfasser: DE ROCHAMBEAU, Donatien, SUN, Yuanye, SLEIMAN, Hanadi F
Format: Patent
Sprache:eng ; fre ; ger
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