EFFECTIVE METHOD FOR MANUFACTURING ANTIBODY-DRUG CONJUGATE

A method for producing an antibody-drug conjugate in which a drug-linker represented by formula (1) (wherein A represents the connecting position to an antibody) is conjugated to the antibody via a thioether bond, wherein the method comprising the steps of: (i) reducing the antibody with a reducing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SAKURATANI Kenji, YAMAGUCHI Tatsuya
Format: Patent
Sprache:eng ; fre ; ger
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