THERAPEUTIC EFFICACY BY PULMONARY DELIVERY OF LIVE ATTENUATED MYCOBACTERIA

The present invention is directed to a live-attenuated Mycobacterium tuberculosis composition comprising an isolated microorganism belonging to a M. tuberculosis MTBVAC strain having a i) PhoP- phenotype by the inactivation by a genetic deletion of the Rv0757 gene, wherein the open-reading frame (OR...

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Bibliographische Detailangaben
Hauptverfasser:	MARTÍN MONTAÑES, Carlos, URANGA MAÍZ, Santiago, VANEVA MARINOVA, Dessislava, TARANCÓN ÍÑIGUEZ, Raquel, AGUILÓ, Juan Ignacio, MATA LOZANO, Elena
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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