ANTIBODIES BINDING TO VISTA AT ACIDIC PH
The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significa...
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| creator | SU, Lin Hui KORMAN, Alan J SHEPPARD, Paul O CRITTON, David A RAJPAL, Arvind DENG, Xiaodi BORGES, Luis RANKIN, Andrew HUANG, Richard Y CHEN, Guodong JOHNSTON, Robert J DEYANOVA, Ekaterina G PINCKNEY, Jason R BAHJAT, Keith Sadoon RAKESTRAW, Ginger |
| description | The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH. |
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In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | ANTIBODIES BINDING TO VISTA AT ACIDIC PH |
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