ANTI-CXCR4 ANTIBODY COMBINED WITH ACTIVATED AND EXPANDED NATURAL KILLER CELLS FOR CANCER IMMUNOTHERAPY

This disclosure provides a method for treating a subject afflicted with a cancer comprising administering to the subject a combination of therapeutically effective amounts of an isolated population of natural killer (NK) cells, preferably activated and expanded NK (NKAE) cells, and an antibody or an...

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Hauptverfasser: PÉREZ MARTÍNEZ, Antonio, VALENTÌN QUIROGA, Jaime, FERNÁNDEZ CASANOVA, Lucía, VELA CUENCA, María, ESCUDERO LÓPEZ, Adela, GONZÀLEZ NAVARRO, Pablo
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creator PÉREZ MARTÍNEZ, Antonio
VALENTÌN QUIROGA, Jaime
FERNÁNDEZ CASANOVA, Lucía
VELA CUENCA, María
ESCUDERO LÓPEZ, Adela
GONZÀLEZ NAVARRO, Pablo
description This disclosure provides a method for treating a subject afflicted with a cancer comprising administering to the subject a combination of therapeutically effective amounts of an isolated population of natural killer (NK) cells, preferably activated and expanded NK (NKAE) cells, and an antibody or an antigen-binding portion thereof that binds specifically to C-X-C Chemokine Receptor 4 (CXCR4) expressed on the surface of a cancer cell.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTI-CXCR4 ANTIBODY COMBINED WITH ACTIVATED AND EXPANDED NATURAL KILLER CELLS FOR CANCER IMMUNOTHERAPY
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