METHODS OF ACUTE RESTORATION OF VASCULAR COMPLIANCE

Disclosed herein is a compound comprising a 4-amino-1,8-naphthalimide for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque, as well as acutely restoring the vascular compliance at the treatment site of the blood v...

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Hauptverfasser: HABERER, Barbara R, UTECHT, Ronald E, DOWNEY, Therese J
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creator HABERER, Barbara R
UTECHT, Ronald E
DOWNEY, Therese J
description Disclosed herein is a compound comprising a 4-amino-1,8-naphthalimide for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque, as well as acutely restoring the vascular compliance at the treatment site of the blood vessel, while maintaining luminal gain during angioplasty . Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed.
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subjects ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
RADIATION THERAPY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
ULTRASOUND THERAPY
title METHODS OF ACUTE RESTORATION OF VASCULAR COMPLIANCE
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