BISPECIFIC ANTIBODY CONSTRUCT DIRECTED TO MUC17 AND CD3
The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the Macaca CD3E chain and optionally a third domain, which is a specific Fc modality. Moreover, the inventio...
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| creator | ROSS, Sandra RAUM, Tobias PENDZIALEK, Jochen CHEN, Irwin WAHI, Joachim BLÜMEL, Claudia DAHLHOFF, Christoph NAHRWOLD, Elisabeth BAILIS, Julie ARVEDSON, Tara |
| description | The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the Macaca CD3E chain and optionally a third domain, which is a specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same. |
| format | Patent |
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Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201104&DB=EPODOC&CC=EP&NR=3732200A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201104&DB=EPODOC&CC=EP&NR=3732200A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROSS, Sandra</creatorcontrib><creatorcontrib>RAUM, Tobias</creatorcontrib><creatorcontrib>PENDZIALEK, Jochen</creatorcontrib><creatorcontrib>CHEN, Irwin</creatorcontrib><creatorcontrib>WAHI, Joachim</creatorcontrib><creatorcontrib>BLÜMEL, Claudia</creatorcontrib><creatorcontrib>DAHLHOFF, Christoph</creatorcontrib><creatorcontrib>NAHRWOLD, Elisabeth</creatorcontrib><creatorcontrib>BAILIS, Julie</creatorcontrib><creatorcontrib>ARVEDSON, Tara</creatorcontrib><title>BISPECIFIC ANTIBODY CONSTRUCT DIRECTED TO MUC17 AND CD3</title><description>The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the Macaca CD3E chain and optionally a third domain, which is a specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB38gwOcHX2dPN0VnD0C_F08neJVHD29wsOCQp1DlFw8QxydQ5xdVEI8VfwDXU2NAcqclFwdjHmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgHG5sZGRgYGjobGRCgBAMJ_Jzk</recordid><startdate>20201104</startdate><enddate>20201104</enddate><creator>ROSS, Sandra</creator><creator>RAUM, Tobias</creator><creator>PENDZIALEK, Jochen</creator><creator>CHEN, Irwin</creator><creator>WAHI, Joachim</creator><creator>BLÜMEL, Claudia</creator><creator>DAHLHOFF, Christoph</creator><creator>NAHRWOLD, Elisabeth</creator><creator>BAILIS, Julie</creator><creator>ARVEDSON, Tara</creator><scope>EVB</scope></search><sort><creationdate>20201104</creationdate><title>BISPECIFIC ANTIBODY CONSTRUCT DIRECTED TO MUC17 AND CD3</title><author>ROSS, Sandra ; RAUM, Tobias ; PENDZIALEK, Jochen ; CHEN, Irwin ; WAHI, Joachim ; BLÜMEL, Claudia ; DAHLHOFF, Christoph ; NAHRWOLD, Elisabeth ; BAILIS, Julie ; ARVEDSON, Tara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3732200A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ROSS, Sandra</creatorcontrib><creatorcontrib>RAUM, Tobias</creatorcontrib><creatorcontrib>PENDZIALEK, Jochen</creatorcontrib><creatorcontrib>CHEN, Irwin</creatorcontrib><creatorcontrib>WAHI, Joachim</creatorcontrib><creatorcontrib>BLÜMEL, Claudia</creatorcontrib><creatorcontrib>DAHLHOFF, Christoph</creatorcontrib><creatorcontrib>NAHRWOLD, Elisabeth</creatorcontrib><creatorcontrib>BAILIS, Julie</creatorcontrib><creatorcontrib>ARVEDSON, Tara</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROSS, Sandra</au><au>RAUM, Tobias</au><au>PENDZIALEK, Jochen</au><au>CHEN, Irwin</au><au>WAHI, Joachim</au><au>BLÜMEL, Claudia</au><au>DAHLHOFF, Christoph</au><au>NAHRWOLD, Elisabeth</au><au>BAILIS, Julie</au><au>ARVEDSON, Tara</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BISPECIFIC ANTIBODY CONSTRUCT DIRECTED TO MUC17 AND CD3</title><date>2020-11-04</date><risdate>2020</risdate><abstract>The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the Macaca CD3E chain and optionally a third domain, which is a specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BISPECIFIC ANTIBODY CONSTRUCT DIRECTED TO MUC17 AND CD3 |
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