ANTIBODIES AGAINST CD73 AND USES THEREOF

The present invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to human Cluster of Differentiation 73 (CD73) with high affinity, and inhibit the activity of CD73, and optionally mediate antibody dependent CD73 internalization. Nucleic acid molecules encoding...

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Hauptverfasser:	MYERS, Joseph E, SCHWEIZER, Liang, KORMAN, Alan J, HATCHER, Sandra V, SEGA, Emanuela, HUANG, Richard, LEI, Ming, LONBERG, Nils, SRINIVASAN, Mohan, BARNHART, Bryan C, HUANG, Haichun, YAMNIUK, Aaron P, JURE-KUNKEL, Maria N, CHEN, Guodong, CORBETT, Martin J, SACK, John, HENNING, Karla A, ZHANG, Pingping, GOODENOUGH, Angela
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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