HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and...
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| creator | BURRI, Raghunadha Reddy KANAGARAJ, Subramaniam SAMANTA, Swapan Kumar NAGARAJU, Nagendra MOHD, Zainuddin RAJAGOPAL, Sridharan SWAMY, Indu N SARKAR, Sayantani GARAPATY, Shivani SIVANANDHAN, Dhanalakshmi NATARAJAN, Tamizharasan THAKUR, Manish Kumar Hariprakash VADIVELU, Saravanan |
| description | The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therapeutic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like. |
| format | Patent |
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These compounds inhibit PRMT5 and are useful as therapeutic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS |
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