DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN

DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN

The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neurorecep...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: IZYKENOVA, Galina Alexandrovna, DAMBINOVA, Svetlana Alexandrovna, GUSEV, Evgeny Ivanovich, SKOROMETS, Alexandr Anisimovich, MARTYNOV, Mikhail Yurievich
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator IZYKENOVA, Galina Alexandrovna
DAMBINOVA, Svetlana Alexandrovna
GUSEV, Evgeny Ivanovich
SKOROMETS, Alexandr Anisimovich
MARTYNOV, Mikhail Yurievich
description The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3657175A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3657175A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3657175A13</originalsourceid><addsrcrecordid>eNqNyrEKwjAQANAsDqL-w_2AQym1c0wvyUHNlcsNbqVInEQL9f-xgh_g9Ja3NdeObEiclRxkVGAPgjZg0gyeBTpUdEopgIvCaV2D1cg9B8L83Q4Fz2J7oOwiXtbAQoHS3mzu02Mph587Ax7VxWOZX2NZ5ulWnuU94lCfmrZqG1vVf5QPeA4wrw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN</title><source>esp@cenet</source><creator>IZYKENOVA, Galina Alexandrovna ; DAMBINOVA, Svetlana Alexandrovna ; GUSEV, Evgeny Ivanovich ; SKOROMETS, Alexandr Anisimovich ; MARTYNOV, Mikhail Yurievich</creator><creatorcontrib>IZYKENOVA, Galina Alexandrovna ; DAMBINOVA, Svetlana Alexandrovna ; GUSEV, Evgeny Ivanovich ; SKOROMETS, Alexandr Anisimovich ; MARTYNOV, Mikhail Yurievich</creatorcontrib><description>The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.</description><language>eng ; fre ; ger</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200527&amp;DB=EPODOC&amp;CC=EP&amp;NR=3657175A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200527&amp;DB=EPODOC&amp;CC=EP&amp;NR=3657175A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>IZYKENOVA, Galina Alexandrovna</creatorcontrib><creatorcontrib>DAMBINOVA, Svetlana Alexandrovna</creatorcontrib><creatorcontrib>GUSEV, Evgeny Ivanovich</creatorcontrib><creatorcontrib>SKOROMETS, Alexandr Anisimovich</creatorcontrib><creatorcontrib>MARTYNOV, Mikhail Yurievich</creatorcontrib><title>DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN</title><description>The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w_2AQym1c0wvyUHNlcsNbqVInEQL9f-xgh_g9Ja3NdeObEiclRxkVGAPgjZg0gyeBTpUdEopgIvCaV2D1cg9B8L83Q4Fz2J7oOwiXtbAQoHS3mzu02Mph587Ax7VxWOZX2NZ5ulWnuU94lCfmrZqG1vVf5QPeA4wrw</recordid><startdate>20200527</startdate><enddate>20200527</enddate><creator>IZYKENOVA, Galina Alexandrovna</creator><creator>DAMBINOVA, Svetlana Alexandrovna</creator><creator>GUSEV, Evgeny Ivanovich</creator><creator>SKOROMETS, Alexandr Anisimovich</creator><creator>MARTYNOV, Mikhail Yurievich</creator><scope>EVB</scope></search><sort><creationdate>20200527</creationdate><title>DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN</title><author>IZYKENOVA, Galina Alexandrovna ; DAMBINOVA, Svetlana Alexandrovna ; GUSEV, Evgeny Ivanovich ; SKOROMETS, Alexandr Anisimovich ; MARTYNOV, Mikhail Yurievich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3657175A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>IZYKENOVA, Galina Alexandrovna</creatorcontrib><creatorcontrib>DAMBINOVA, Svetlana Alexandrovna</creatorcontrib><creatorcontrib>GUSEV, Evgeny Ivanovich</creatorcontrib><creatorcontrib>SKOROMETS, Alexandr Anisimovich</creatorcontrib><creatorcontrib>MARTYNOV, Mikhail Yurievich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IZYKENOVA, Galina Alexandrovna</au><au>DAMBINOVA, Svetlana Alexandrovna</au><au>GUSEV, Evgeny Ivanovich</au><au>SKOROMETS, Alexandr Anisimovich</au><au>MARTYNOV, Mikhail Yurievich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN</title><date>2020-05-27</date><risdate>2020</risdate><abstract>The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP3657175A1
source esp@cenet
subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title DIAGNOSTIC SET OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF CEREBRAL ISCHEMIC ORIGIN
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T18%3A16%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=IZYKENOVA,%20Galina%20Alexandrovna&rft.date=2020-05-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3657175A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true