PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF OBETICHOLIC ACID AND DERIVATIVES THEREOF

The invention relates to a process for the preparation of obeticholic acid and derivatives thereof comprising: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereof to obtain a compound of formula (IIIa) and/or (IIIb), or...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	CORDOVILLA LOSADA, Carlos, HERRÁIZ SIERRA, Ignacio, PÉREZ ENCABO, Alfonso, FERNÁNDEZ SAINZ, Yolanda, TURIEL HERNANDEZ, José Angel
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
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