QUINAZOLINE-PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER-RELATED DISORDERS

A compound that is an inhibitor of at least one of the A2A and A2B adenosine receptors having Formula (I)and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of disease...

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Hauptverfasser: LELETI, Manmohan Reddy, POWERS, Jay Patrick, MILES, Dillon Harding, ROSEN, Brandon Reid, SHARIF, Ehesan Ul
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creator LELETI, Manmohan Reddy
POWERS, Jay Patrick
MILES, Dillon Harding
ROSEN, Brandon Reid
SHARIF, Ehesan Ul
description A compound that is an inhibitor of at least one of the A2A and A2B adenosine receptors having Formula (I)and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2A receptor and/or the adenosine A2B receptor.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title QUINAZOLINE-PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER-RELATED DISORDERS
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