METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND

METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND

The aim of the present invention is to provide a method capable of producing an optically active pyrimidinamide derivative on an industrial scale.Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the obtained compound (II) or a salt thereof is subjected to a deprotecti...

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Hauptverfasser: IKEUCHI, Motoki, TAKEDA, Yoshiyuki, KAWAKAMI, Jun-ichi, KITAYAMA, Masato, NAKAMOTO, Koji, YAMADA, Masatoshi, HIRANO, Sayuri
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator IKEUCHI, Motoki
TAKEDA, Yoshiyuki
KAWAKAMI, Jun-ichi
KITAYAMA, Masato
NAKAMOTO, Koji
YAMADA, Masatoshi
HIRANO, Sayuri
description The aim of the present invention is to provide a method capable of producing an optically active pyrimidinamide derivative on an industrial scale.Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the obtained compound (II) or a salt thereof is subjected to a deprotection reaction, and the obtained compound (III) or a salt thereof is reacted with compound (VI) or a salt thereof to obtain compound (V) or a salt thereof.wherein each symbol is as defined in the specification.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND
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