COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA-1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF

COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA-1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF

Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concent...

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Hauptverfasser: ZIMMERMAN, THOMAS P, StPETER, MICHELLE, MILLER, CHARLES, KLOS, ANTHONY, ALLGAIER, ERIC, GLANCY, KELLY, REBBEOR, JAMES, WEE, KEVIN
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator ZIMMERMAN, THOMAS P
StPETER, MICHELLE
MILLER, CHARLES
KLOS, ANTHONY
ALLGAIER, ERIC
GLANCY, KELLY
REBBEOR, JAMES
WEE, KEVIN
description Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA-1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF
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