METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS

The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhib...

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Bibliographische Detailangaben
Hauptverfasser: Meyerson, Matthew, Sellers, William R, Bell, Daphne Winifred, Janne, Pasi Antero, Paez, Juan Guillermo, Johnson, Bruce E, Sordella, Raffaella, Settleman, Jeffrey E, Haber, Daniel A, Lynch, Thomas J
Format: Patent
Sprache:eng ; fre ; ger
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