METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME
It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell popu...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NAKAISHI Tomoyuki MOUTAI Tatsuya KITAMURA Daisuke KITA Hiroshi KITANO Mitsuaki |
| description | It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by Fas to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3569700B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3569700B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3569700B13</originalsourceid><addsrcrecordid>eNrjZEjydQ3x8HdRcPMPUggI8ncJdfb0c1dwUnB29fFRCPAPCPVxDPH091Nw9HNRwKrU19_P39nH38_RB6gmxNPJ3yVSITQYJBPi4aoQ7OjrysPAmpaYU5zKC6W5GRTcXEOcPXRTC_LjU4sLEpNT81JL4l0DjE3NLM0NDJwMjYlQAgBpsDNu</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME</title><source>esp@cenet</source><creator>NAKAISHI Tomoyuki ; MOUTAI Tatsuya ; KITAMURA Daisuke ; KITA Hiroshi ; KITANO Mitsuaki</creator><creatorcontrib>NAKAISHI Tomoyuki ; MOUTAI Tatsuya ; KITAMURA Daisuke ; KITA Hiroshi ; KITANO Mitsuaki</creatorcontrib><description>It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by Fas to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230913&DB=EPODOC&CC=EP&NR=3569700B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230913&DB=EPODOC&CC=EP&NR=3569700B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NAKAISHI Tomoyuki</creatorcontrib><creatorcontrib>MOUTAI Tatsuya</creatorcontrib><creatorcontrib>KITAMURA Daisuke</creatorcontrib><creatorcontrib>KITA Hiroshi</creatorcontrib><creatorcontrib>KITANO Mitsuaki</creatorcontrib><title>METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME</title><description>It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by Fas to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZEjydQ3x8HdRcPMPUggI8ncJdfb0c1dwUnB29fFRCPAPCPVxDPH091Nw9HNRwKrU19_P39nH38_RB6gmxNPJ3yVSITQYJBPi4aoQ7OjrysPAmpaYU5zKC6W5GRTcXEOcPXRTC_LjU4sLEpNT81JL4l0DjE3NLM0NDJwMjYlQAgBpsDNu</recordid><startdate>20230913</startdate><enddate>20230913</enddate><creator>NAKAISHI Tomoyuki</creator><creator>MOUTAI Tatsuya</creator><creator>KITAMURA Daisuke</creator><creator>KITA Hiroshi</creator><creator>KITANO Mitsuaki</creator><scope>EVB</scope></search><sort><creationdate>20230913</creationdate><title>METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME</title><author>NAKAISHI Tomoyuki ; MOUTAI Tatsuya ; KITAMURA Daisuke ; KITA Hiroshi ; KITANO Mitsuaki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3569700B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>NAKAISHI Tomoyuki</creatorcontrib><creatorcontrib>MOUTAI Tatsuya</creatorcontrib><creatorcontrib>KITAMURA Daisuke</creatorcontrib><creatorcontrib>KITA Hiroshi</creatorcontrib><creatorcontrib>KITANO Mitsuaki</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NAKAISHI Tomoyuki</au><au>MOUTAI Tatsuya</au><au>KITAMURA Daisuke</au><au>KITA Hiroshi</au><au>KITANO Mitsuaki</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME</title><date>2023-09-13</date><risdate>2023</risdate><abstract>It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by Fas to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3569700B1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | METHOD FOR PRODUCING B CELL POPULATION AND METHOD FOR PRODUCING MONOCLONAL ANTIBODY USING THE SAME |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T17%3A07%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NAKAISHI%20Tomoyuki&rft.date=2023-09-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3569700B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |