CLEARING AGENT

It is an object of the present invention to provide a clearing agent, by which after a fusion of the streptavidin mutant and a molecular probe has been administered, the fusion, which is not localized in a target site such as an affected site but remains in the body, can be promptly removed (cleared...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: TSUKAGOSHI Masanobu
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:It is an object of the present invention to provide a clearing agent, by which after a fusion of the streptavidin mutant and a molecular probe has been administered, the fusion, which is not localized in a target site such as an affected site but remains in the body, can be promptly removed (cleared) from the body. The present invention provides a compound represented by the following formula (1) or a salt thereof:wherein X1a, X1b, X2a and X2b each independently represent O or NH; Yand Yeach independently represent C or S; Zand Zeach independently represent O, S or NH; Vand Veach independently represent S or S-O; n1 and n2 each independently represent an integer of 0 or 1; L10 and L12 each independently represent a divalent linking group; L11 represents a trivalent linking group; L14 represents a divalent linking group; and Sugar represents a sugar residue.