DEVICES AND METHODS FOR SAMPLE ANALYSIS

Integrated devices (30; 40; 100; 101; 600); that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet wi...

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Bibliographische Detailangaben
Hauptverfasser: HAYDEN, Mark A, ROBINSON, John, HOLETS-MCCORMACK, Shelley R, FISCHER, Andrew, LAURENSON, Sophie, HUFF, Jeffrey B
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Integrated devices (30; 40; 100; 101; 600); that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. The detection modules disclosed here can be used for detecting analytes of interest which analytes may have been enriched by amplification, isolation, or other techniques.