THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS

The present invention relates to thienopyrimidine compound, preparation method thereof, pharmaceutical composition and use thereof, and in particular to a type of compounds having ALK and/or c-Met selective inhibitory activity, a method for the preparation thereof, a pharmaceutical composition compr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LI, Li, DENG, Xianming, LI, Yunzhan, LIU, Shuang, ZHANG, Baoding, LU, Yue, DONG, Chao, DENG, Zhou, HU, Zhiyu, SUN, Xihuan, HUANG, Xiaoxing
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator LI, Li
DENG, Xianming
LI, Yunzhan
LIU, Shuang
ZHANG, Baoding
LU, Yue
DONG, Chao
DENG, Zhou
HU, Zhiyu
SUN, Xihuan
HUANG, Xiaoxing
description The present invention relates to thienopyrimidine compound, preparation method thereof, pharmaceutical composition and use thereof, and in particular to a type of compounds having ALK and/or c-Met selective inhibitory activity, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with anaplastic lymphoma kinaseand in the manufacture of a medicament for preventing or treating a disease associated with angiogenesis or cancer metastasis, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3498716A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3498716A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3498716A43</originalsourceid><addsrcrecordid>eNqNi00KwjAQRrtxIeod5gB1IS3-LIdkSgaaZEjTRVelaFyJFur9sUUP4OqD9963zm7RMDkvXWDLmh2B8lZ863QOEkgwYGTvwFI0XkM0FKjyYZYGg0VFbWSF9ffV8NLmgE4DitSzWUCzzVb34TGl3W83GVQUldmn8dWnaRyu6ZnePUlRXs6nwxHL4o_kAz-jNMU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS</title><source>esp@cenet</source><creator>LI, Li ; DENG, Xianming ; LI, Yunzhan ; LIU, Shuang ; ZHANG, Baoding ; LU, Yue ; DONG, Chao ; DENG, Zhou ; HU, Zhiyu ; SUN, Xihuan ; HUANG, Xiaoxing</creator><creatorcontrib>LI, Li ; DENG, Xianming ; LI, Yunzhan ; LIU, Shuang ; ZHANG, Baoding ; LU, Yue ; DONG, Chao ; DENG, Zhou ; HU, Zhiyu ; SUN, Xihuan ; HUANG, Xiaoxing</creatorcontrib><description>The present invention relates to thienopyrimidine compound, preparation method thereof, pharmaceutical composition and use thereof, and in particular to a type of compounds having ALK and/or c-Met selective inhibitory activity, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with anaplastic lymphoma kinaseand in the manufacture of a medicament for preventing or treating a disease associated with angiogenesis or cancer metastasis, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200325&amp;DB=EPODOC&amp;CC=EP&amp;NR=3498716A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200325&amp;DB=EPODOC&amp;CC=EP&amp;NR=3498716A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI, Li</creatorcontrib><creatorcontrib>DENG, Xianming</creatorcontrib><creatorcontrib>LI, Yunzhan</creatorcontrib><creatorcontrib>LIU, Shuang</creatorcontrib><creatorcontrib>ZHANG, Baoding</creatorcontrib><creatorcontrib>LU, Yue</creatorcontrib><creatorcontrib>DONG, Chao</creatorcontrib><creatorcontrib>DENG, Zhou</creatorcontrib><creatorcontrib>HU, Zhiyu</creatorcontrib><creatorcontrib>SUN, Xihuan</creatorcontrib><creatorcontrib>HUANG, Xiaoxing</creatorcontrib><title>THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS</title><description>The present invention relates to thienopyrimidine compound, preparation method thereof, pharmaceutical composition and use thereof, and in particular to a type of compounds having ALK and/or c-Met selective inhibitory activity, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with anaplastic lymphoma kinaseand in the manufacture of a medicament for preventing or treating a disease associated with angiogenesis or cancer metastasis, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi00KwjAQRrtxIeod5gB1IS3-LIdkSgaaZEjTRVelaFyJFur9sUUP4OqD9963zm7RMDkvXWDLmh2B8lZ863QOEkgwYGTvwFI0XkM0FKjyYZYGg0VFbWSF9ffV8NLmgE4DitSzWUCzzVb34TGl3W83GVQUldmn8dWnaRyu6ZnePUlRXs6nwxHL4o_kAz-jNMU</recordid><startdate>20200325</startdate><enddate>20200325</enddate><creator>LI, Li</creator><creator>DENG, Xianming</creator><creator>LI, Yunzhan</creator><creator>LIU, Shuang</creator><creator>ZHANG, Baoding</creator><creator>LU, Yue</creator><creator>DONG, Chao</creator><creator>DENG, Zhou</creator><creator>HU, Zhiyu</creator><creator>SUN, Xihuan</creator><creator>HUANG, Xiaoxing</creator><scope>EVB</scope></search><sort><creationdate>20200325</creationdate><title>THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS</title><author>LI, Li ; DENG, Xianming ; LI, Yunzhan ; LIU, Shuang ; ZHANG, Baoding ; LU, Yue ; DONG, Chao ; DENG, Zhou ; HU, Zhiyu ; SUN, Xihuan ; HUANG, Xiaoxing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3498716A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI, Li</creatorcontrib><creatorcontrib>DENG, Xianming</creatorcontrib><creatorcontrib>LI, Yunzhan</creatorcontrib><creatorcontrib>LIU, Shuang</creatorcontrib><creatorcontrib>ZHANG, Baoding</creatorcontrib><creatorcontrib>LU, Yue</creatorcontrib><creatorcontrib>DONG, Chao</creatorcontrib><creatorcontrib>DENG, Zhou</creatorcontrib><creatorcontrib>HU, Zhiyu</creatorcontrib><creatorcontrib>SUN, Xihuan</creatorcontrib><creatorcontrib>HUANG, Xiaoxing</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI, Li</au><au>DENG, Xianming</au><au>LI, Yunzhan</au><au>LIU, Shuang</au><au>ZHANG, Baoding</au><au>LU, Yue</au><au>DONG, Chao</au><au>DENG, Zhou</au><au>HU, Zhiyu</au><au>SUN, Xihuan</au><au>HUANG, Xiaoxing</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS</title><date>2020-03-25</date><risdate>2020</risdate><abstract>The present invention relates to thienopyrimidine compound, preparation method thereof, pharmaceutical composition and use thereof, and in particular to a type of compounds having ALK and/or c-Met selective inhibitory activity, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with anaplastic lymphoma kinaseand in the manufacture of a medicament for preventing or treating a disease associated with angiogenesis or cancer metastasis, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP3498716A4
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T02%3A41%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LI,%20Li&rft.date=2020-03-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3498716A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true