METHOD FOR PREPARING 4-(PIPERIDIN-4-YL)MORPHOLINE

METHOD FOR PREPARING 4-(PIPERIDIN-4-YL)MORPHOLINE

The object of the present invention is to provide a method for preparing 4-(piperidin-4-yl)morpholine, which is easy to operate. The object can be solved by a method for preparing 4-(1-benzylpiperidin-4-yl)morpholine, characterized in that 5-fold molar or more of morpholine is added to 1-benzyl-4-pi...

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Hauptverfasser: ISHIKAWA Hiromi, NAKAGAWA Kiyono, TAKEDA Yukiko
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator ISHIKAWA Hiromi
NAKAGAWA Kiyono
TAKEDA Yukiko
description The object of the present invention is to provide a method for preparing 4-(piperidin-4-yl)morpholine, which is easy to operate. The object can be solved by a method for preparing 4-(1-benzylpiperidin-4-yl)morpholine, characterized in that 5-fold molar or more of morpholine is added to 1-benzyl-4-piperidone, and the mixture is reacted with hydrogen under 1 MPa or less in the presence of platinum catalyst or palladium catalyst.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title METHOD FOR PREPARING 4-(PIPERIDIN-4-YL)MORPHOLINE
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