IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS

IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS

Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each elect...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HANNAMAN, Andrew W, MASTERSON, Steven P, BERNARD, Robert M
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
RADIATION THERAPY
ULTRASOUND THERAPY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator HANNAMAN, Andrew W
MASTERSON, Steven P
BERNARD, Robert M
description Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes a least in their deployed state.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3466483A9</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3466483A9</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3466483A93</originalsourceid><addsrcrecordid>eNqNyrEKwjAQANAsDqL-w_1Ap5Si45Fc2mBqwvVa6FSKxKloof4_OvgBTm95e3X1beI4kAVMCRml78BFBgpkhL3BEEZoyXqU77EU_EA8QnQgDTEm6sUbwJpu0h3V7jEvWz79PChwJKYp8vqa8rbO9_zM74mSLquqPGu86D_KB1bwLZ8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS</title><source>esp@cenet</source><creator>HANNAMAN, Andrew W ; MASTERSON, Steven P ; BERNARD, Robert M</creator><creatorcontrib>HANNAMAN, Andrew W ; MASTERSON, Steven P ; BERNARD, Robert M</creatorcontrib><description>Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes a least in their deployed state.</description><language>eng ; fre ; ger</language><subject>ELECTROTHERAPY ; HUMAN NECESSITIES ; HYGIENE ; MAGNETOTHERAPY ; MEDICAL OR VETERINARY SCIENCE ; RADIATION THERAPY ; ULTRASOUND THERAPY</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200311&amp;DB=EPODOC&amp;CC=EP&amp;NR=3466483A9$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200311&amp;DB=EPODOC&amp;CC=EP&amp;NR=3466483A9$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HANNAMAN, Andrew W</creatorcontrib><creatorcontrib>MASTERSON, Steven P</creatorcontrib><creatorcontrib>BERNARD, Robert M</creatorcontrib><title>IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS</title><description>Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes a least in their deployed state.</description><subject>ELECTROTHERAPY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MAGNETOTHERAPY</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>RADIATION THERAPY</subject><subject>ULTRASOUND THERAPY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w_1Ap5Si45Fc2mBqwvVa6FSKxKloof4_OvgBTm95e3X1beI4kAVMCRml78BFBgpkhL3BEEZoyXqU77EU_EA8QnQgDTEm6sUbwJpu0h3V7jEvWz79PChwJKYp8vqa8rbO9_zM74mSLquqPGu86D_KB1bwLZ8</recordid><startdate>20200311</startdate><enddate>20200311</enddate><creator>HANNAMAN, Andrew W</creator><creator>MASTERSON, Steven P</creator><creator>BERNARD, Robert M</creator><scope>EVB</scope></search><sort><creationdate>20200311</creationdate><title>IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS</title><author>HANNAMAN, Andrew W ; MASTERSON, Steven P ; BERNARD, Robert M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3466483A93</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>ELECTROTHERAPY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MAGNETOTHERAPY</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>RADIATION THERAPY</topic><topic>ULTRASOUND THERAPY</topic><toplevel>online_resources</toplevel><creatorcontrib>HANNAMAN, Andrew W</creatorcontrib><creatorcontrib>MASTERSON, Steven P</creatorcontrib><creatorcontrib>BERNARD, Robert M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HANNAMAN, Andrew W</au><au>MASTERSON, Steven P</au><au>BERNARD, Robert M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS</title><date>2020-03-11</date><risdate>2020</risdate><abstract>Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes a least in their deployed state.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP3466483A9
source esp@cenet
subjects ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
RADIATION THERAPY
ULTRASOUND THERAPY
title IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T00%3A45%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HANNAMAN,%20Andrew%20W&rft.date=2020-03-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3466483A9%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true