ASSESSMENT OF JAK-STAT1/2 CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION
The present invention relates to a computer-implemented method for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject based on expression levels of three or more target genes of the JAK-STAT1/2 cellular signaling pathway measured in a sample of the subject. The present inven...
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| creator | VAN DE STOLPE, Anja DOU, Meng VERHAEGH, Wilhelmus Franciscus Johannes VELTER, Rick |
| description | The present invention relates to a computer-implemented method for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject based on expression levels of three or more target genes of the JAK-STAT1/2 cellular signaling pathway measured in a sample of the subject. The present invention further relates to an apparatus, to a non-transitory storage medium, and to a computer program for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject. The present invention further relates to a kit for measuring expression levels of three or more target genes of the JAK-STAT1/2 cellular signaling pathway in a sample of a subject, to a kit for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject, and to the use of such kits in performing the method. |
| format | Patent |
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The present invention further relates to an apparatus, to a non-transitory storage medium, and to a computer program for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject. The present invention further relates to a kit for measuring expression levels of three or more target genes of the JAK-STAT1/2 cellular signaling pathway in a sample of a subject, to a kit for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject, and to the use of such kits in performing the method.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190403&DB=EPODOC&CC=EP&NR=3461915A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190403&DB=EPODOC&CC=EP&NR=3461915A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VAN DE STOLPE, Anja</creatorcontrib><creatorcontrib>DOU, Meng</creatorcontrib><creatorcontrib>VERHAEGH, Wilhelmus Franciscus Johannes</creatorcontrib><creatorcontrib>VELTER, Rick</creatorcontrib><title>ASSESSMENT OF JAK-STAT1/2 CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION</title><description>The present invention relates to a computer-implemented method for inferring activity of a JAK-STAT1/2 cellular signaling pathway in a subject based on expression levels of three or more target genes of the JAK-STAT1/2 cellular signaling pathway measured in a sample of the subject. 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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | ASSESSMENT OF JAK-STAT1/2 CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION |
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