CANCER CELL BINDING RECOMBINANT LECTINS WITH ANTITUMOR ACTIVITY AND METHOD OF PREPARATION

CANCER CELL BINDING RECOMBINANT LECTINS WITH ANTITUMOR ACTIVITY AND METHOD OF PREPARATION

The present invention discloses genes for new variants in E.coli that are more close to the wild type lectin sequence but still differ in surface charges. This recombinant version (exemplified Rec-2 and Rec-3) are cancer cell binding with anti tumor activity show blood group specificity similar to t...

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Hauptverfasser: CHACHADI, Vishwanath Basavaraj, VENKAT, Hemalatha, INAMDAR, Shashikala Ramchandra, RAMADOSS, Candadai Seshadri, SWAMY, Bale Murugi, NAGRE, Nagaraja Narayan
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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creator CHACHADI, Vishwanath Basavaraj
VENKAT, Hemalatha
INAMDAR, Shashikala Ramchandra
RAMADOSS, Candadai Seshadri
SWAMY, Bale Murugi
NAGRE, Nagaraja Narayan
description The present invention discloses genes for new variants in E.coli that are more close to the wild type lectin sequence but still differ in surface charges. This recombinant version (exemplified Rec-2 and Rec-3) are cancer cell binding with anti tumor activity show blood group specificity similar to the native lectin but retains the stability and the solubility properties.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title CANCER CELL BINDING RECOMBINANT LECTINS WITH ANTITUMOR ACTIVITY AND METHOD OF PREPARATION
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